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Luteinising Hormone
Together with follicle stimulating hormone (FSH),
Luteinising Hormone (LH) is required for the development of a
mature follicle, containing an egg capable of being
fertilised.
It is responsible for final maturation and subsequent ovulation of
the egg and maintains a hormone secreting body called the corpus
luteum – formed at the site of egg expulsion – which provides
support in the early stages of pregnancy.
Although FSH and LH are both necessary for egg maturation, only
very small amounts of LH are needed. The minimal exposure to LH
required for satisfactory egg maturation is called the LH
Threshold. Too little LH, below a threshold level, can lead to
inadequate maturation of eggs and can cause treatment to
fail.
On the other hand, research has shown that excessive exposure to LH
is damaging to egg maturation. The maximum exposure required for
optimal egg maturation is called the LH Ceiling.
There seems to be an Optimal Window for LH activity. The ‘LH
Therapeutic Window’ needs to be precisely targeted, as too little
or too much LH is damaging to the egg.
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